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Registros recuperados: 16
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Antimicrobial activity of linezolid against Gram-positive cocci isolated in Brazil BJID
Sader,Helio S.; Gales,Ana C.; Jones,Ronald N..
The new oxazolidinone linezolid and other antimicrobial agents used to treat Gram-positive infections were tested against 1,585 Gram-positive cocci; 1,260 staphylococci and enterococci isolates from patients hospitalized in Brazilian hospitals, and 325 S. pneumoniae isolates for patients with community acquired infections. Susceptibility testing was performed using broth microdilution according to NCCLS procedures. Linezolid was the most active compound and the only drug that inhibited 100% of the isolates at the susceptible breakpoint (< 4 mg/mL). Resistance to vancomycin was very rare (99.9% susceptibility), and both quinupristin/dalfopristin and gatifloxacin were active against approximately 90% of the strains evaluated. All other compounds inhibited...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Gram-positive cocci; Oxazolidinones; Antimicrobial resistance; Linezolid; Vancomycin resistance; Nosocomial infections.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000400002
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Antimicrobial susceptibility of gram-positive bacteria isolated in brazilian hospitals participating in the SENTRY Program (2005-2008) BJID
Gales,Ana C.; Sader,Helio S.; Ribeiro,Julival; Zoccoli,Cassia; Barth,Afonso; Pignatari,Antonio C..
We report the antimicrobial susceptibility patterns of the most frequently isolated Gram-positive bacteria in the Brazilian hospitals participating in the SENTRYAntimicrobial Surveillance Program. The strains were consecutively collected (one per patient) between January 2005 and September 2008 and susceptibility tested by reference broth microdilution methods at the JMI Laboratories (North Liberty, Iowa, USA). A total of 3,907 Gram-positive cocci were analyzed. The Gram-positive organisms most frequently isolated from bloodstream infections were Staphylococcus aureus (2,218 strains; 20.2% of total), coagulase-negative staphylococci (CoNS; 812 strains [14.7%]), and Enterococcus spp. (754 strains; 5.0%). S. aureus ranked first (28.1%) and Enterococcus...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimicrobial resistance; SENTRY; Nosocomial infections; Brazil.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000200004
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Assessment of hospital daily cleaning practices using ATP bioluminescence in a developing country BJID
Zambrano,Alejandra A.; Jones,Alex; Otero,Paula; Ajenjo,Maria Cristina; Labarca,Jaime A..
Visual assessment of surfaces may not be enough to document the level of cleanliness in the hospital setting. It is necessary to introduce quantitative methods to document the results of this practice.Objective:To evaluate the efficacy of hospital terminal cleaning procedures, using an adenosine triphosphate (ATP) bioluminescence method in a teaching hospital.Method:During 2008 we conducted an evaluation using ATP bioluminescence LIGHTNING MVP™ (Arquimed) of external and internal housekeeping service. After conducting an initial evaluation we implemented education of cleaning practices and finally we did a post intervention evaluation. Using chi-square method we compared prior versus after cleaning, quality of cleaning performed by external versus internal...
Tipo: Info:eu-repo/semantics/report Palavras-chave: ATP bioluminescence; Cleaning; Bacterial resistance; Nosocomial infections.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600675
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Clinical significance of the isolation of Candidaspecies from hospitalized patients BJM
Magalhães,Yankee C.; Bomfim,Maria Rosa Q.; Melônio,Luciane C.; Ribeiro,Patrícia C.S.; Cosme,Lécia M.; Rhoden,Cristianne R.; Marques,Sirlei G..
In this study, we isolated and phenotypically identified 108 yeast strains from various clinical specimens collected from 100 hospitalized patients at three tertiary hospitals in São Luís-Maranhão, Brazil, from July to December 2010. The isolates were analyzed for their susceptibility to four of the most widely used antifungal agents in the surveyed hospitals, amphotericin B, fluconazole, 5-flucytosine and voriconazole. The species identified were Candida albicans (41.4%), Candida tropicalis (30.1%), C. glabrata (7.4%), Candida parapsilosis(5.5%), Candida krusei (4.6%), Cryptococcus neoformans (4.6%), Trichosporonspp. (3.7%), Candida norvegensis (0.9%), Rhodotorula glutinis (0.9%) and Pichia farinosa (0.9%). A higher isolation rate was observed in the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fungal infections; Susceptibility profile; Nosocomial infections.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100117
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Cluster of Candida parapsilosis primary bloodstream infection in a neonatal intensive care unit BJID
Silva,Carmem Lúcia P. da; Santos,Rosana M. R. dos; Colombo,Arnaldo Lopes.
Candida parapsilosis is an increasingly important bloodstream pathogen in neonatal intensive care units (NICU). We investigated a cluster of bloodstream infections in a NICU to determine whether nosocomial transmission occurred. During a 3-day period, 3 premature infants hospitalized in the same unit presented with sepsis caused by C. parapsilosis. Electrophoretic karyotype of the organisms was performed by using pulsed field gel electrophoresis in a countour-clamped homogeneous electric field system. The isolate from 1 newborn could not be typed, and the isolates from the remaining 2 infants had identical patterns. All 3 cases are described. We conclude that nosocomial transmission of C. parapsilosis occurred and that neonates under intensive care may...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candidemia; Nosocomial infections; Neonate.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000100005
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Comparing hospital infections in the elderly versus younger adults: an experience in a Brazilian University Hospital BJID
The elderly population will grow rapidly over the next 25 years, however there is little information about hospital infections in this group of patients in Brazil. We examined the prevalence of nosocomial and community infections in elderly (>65 years) patients and their relationship with intrinsic and extrinsic risk factors in a Brazilian University Hospital. A total of 155 hospitalized elderly patients were evaluated, and clinical and demographic information about each patient was obtained from hospital records. The rates of nosocomial and community infections were 16.1% and 25.6%, respectively. When the elderly group with and without nosocomial infections was analyzed, practically all the risk factors considered (use of antibiotics, invasive devices,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Elderly; Nosocomial infections; Risk factors; Brazilian hospitals; Infection control.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300006
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Detection of cytotoxic activity on Vero cells in clinical isolates of Serratia marcescens BJMBR
Carbonell,G.V.; Alfieri,A.F.; Alfieri,A.A.; Vidotto,M.C.; Levy,C.E.; Darini,A.L.C.; Yanaguita,R.M..
Cytotoxin production was studied in 60 Serratia marcescens strains isolated from hospitalized patients. Association of cytotoxic activity with serotype, source of isolation and presence of plasmids was also evaluated. Thirteen of the 60 S. marcescens strains produced a cytotoxic effect on Vero cells. These strains were isolated from distinct clinical sources and classified into seven different serotypes (O1:H7; O4:NM; O10:NT; O19:NM; O6,14:H4; O6,14:NM and O6,14:H1). No relationship was observed between cytotoxic activity and clinical source or serotypes of the strains. Plasmids from five cytotoxin-producing S. marcescens strains were transferred to E. coli K12/711. The transconjugants did not exhibit cytotoxicity, indicating that the cytotoxic effect is...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytotoxin production; Nosocomial infections; Plasmids; Serratia marcescens; Virulence factors.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001100005
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Nondiphtherial Corynebacterium species isolated from clinical specimens of patients in a university hospital, Rio de Janeiro, Brazil BJM
Camello,Thereza Cristina Ferreira; Mattos-Guaraldi,Ana Luiza; Formiga,Luiz Carlos Duarte; Marques,Elizabeth Andrade.
Over a five-year period, 163 strains of Corynebacterium sp. were recovered from different clinical specimens of patients from a Brazilian University hospital. Genitourinary tract and intravenous sites specimens were the most frequent sources of corynebacteria (46.62%). Corynebacterium amycolatum (29.55%), Corynebacterium minutissimum (20.45%) and Corynebacterium pseudodiphtheriticum (13.63%) were the predominant species found in genitourinary tract. C. minutissimum (24.14%) and Corynebacterium propinquum (17.24%) in surgical and/or other skin wounds and abscesses; Corynebacterium xerosis (25%), C. amycolatum (21.87%) and C. pseudodiphtheriticum (18.75%) in intravenous sites; C. pseudodiphtheriticum (33.33%) and C. propinquum (33.33%) in lower respiratory...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Corynebacterium sp; Nondiphtherial corynebacteria; Nosocomial infections; Multiresistance.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822003000100009
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Nosocomial diarrhea in the intensive care unit BJID
Marcon,Ana Paula; Gamba,Mônica Antar; Vianna,Lucila Amaral Carneiro.
We made an epidemiological case-control study to examine risk factors for the development of diarrhea in the intensive care unit (ICU) of a public hospital in Santo André, SP, from January to October 2002. Forty-nine patients with diarrhea (cases) and 49 patients without diarrhea (controls), matched for age and gender, were included in the study. A stool culture and enzyme immunoassays for Clostridium difficile toxins A and B were performed on fecal specimens from diarrhea patients. Fourteen of them presented positive cultures for Pseudomonas aeruginosa and 22 patients presented positive ELISA for Clostridium diffícile. Nosocomial diarrhea was associated with several factors, including use of antibiotics (P=0.001), use of ceftriaxone (P=0.001), presence of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nosocomial infections; Diarrhea; Antibiotics; Intensive care; Clostridium difficile.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000600005
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Nosocomial infection in a pediatric intensive care unit in a developing country BJID
Abramczyk,Marcelo L.; Carvalho,Werther B.; Carvalho,Eduardo S.; Medeiros,Eduardo A. S..
OBJECTIVE: Determine the rate and outcome of nosocomial infection (NI) in pediatric intensive care unit patients in a developing country. DESIGN: Prospective cohort study using the Centers for Disease Control and Prevention definitions to diagnose nosocomial infection and NNISS (National Nosocomial Infection Surveillance System) methodology. SETTING: São Paulo Hospital - Universidade Federal de São Paulo - Brazil, a 700-bed teaching hospital with an 8-bed pediatric intensive care unit. PARTICIPANTS: All 515 children consecutively admitted to the pediatric intensive care unit from April 1996 to October 1997. RESULTS: The NI incidence was 18.3% and the mean infection rate per 1,000 patient days was 46.1; the ventilator-associated pneumonia rate was 18.7 per...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nosocomial infections; Pediatric ICU; Pneumonia.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000600004
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Nosocomial infections caused by Elizabethkingia meningoseptica: an emergent pathogen BJID
Pereira,Graziella H.; Garcia,Doroti de Oliveira; Abboud,Cely Saad; Barbosa,Vera Lucia de Barros; Silva,Paulo Sérgio Lucas da.
We hereby describe the clinical and epidemiological features and, outcomes of nine patients with Elizabethkingia meningoseptica infections in two hospitals over a 2-year period. All infections caused by this pathogen were nosocomial, or healthcare associated infections, in hemodialysis settings whereas none was correlated with hospital outbreaks.
Tipo: Info:eu-repo/semantics/other Palavras-chave: Elizabethkingia meningoseptica; Nosocomial infections; Bloodstream infections.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500015
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Nosocomial infections in human immunodeficiency virus type 1 (HIV-1) infected and AIDS patients: major microorganisms and immunological profile BJM
Panis,C.; Matsuo,T.; Reiche,E.M.V..
Antiretroviral therapy advances have proportioned to AIDS patients a survival increase. At the same time, the permanence of the seropositive people in the nosocomial environment becomes common not only by the adverse reactions caused by this therapy, but also by several opportunistic diseases that take them into and out of hospital environment. During the hospital permanence, the patients expose their impaired immune system to the nosocomial virulent microorganisms, and acquire destructive nosocomial infections that sometimes can be lethal. Among several hospital syndromes described, little is known about infections in immunocompromised patients and how their immune system is able to determine the course of the infection. The objective of this study was to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: AIDS; CD4+ T cell counts; Nosocomial infections; Immunocompromised.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000100027
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Polyclonal endemicity of Pseudomonas aeruginosa in a teaching hospital from Brazil: molecular typing of decade-old strains J. Venom. Anim. Toxins incl. Trop. Dis.
Fortaleza,CMCB; Bacchi,CE; Oliveira,DE; Ramos,MC.
Pseudomonas aeruginosa infections cause significant mortality and morbidity in health care settings. Strategies to prevent and control the emergence and spread of P. aeruginosa within hospitals involve implementation of barrier methods and antimicrobial stewardship programs. However, there is still much debate over which of these measures holds the utmost importance. Molecular strain typing may help elucidate this issue. In our study, 71 nosocomial isolates from 41 patients and 23 community-acquired isolates from 21 patients were genotyped. Enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) was performed. Band patterns were compared using similarity coefficients of Dice, Jaccard and simple matching. Strain similarity for...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pseudomonas aeruginosa; Strain typing; ERIC-PCR; Nosocomial infections; Health care infections.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200008
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Risk factors for infection by extended-spectrum beta-lactamase producing Klebsiella pneumoniae in a tertiary hospital in Salvador, Brazil BJID
Silva,Nanci; Oliveira,Márcio; Bandeira,Antonio Carlos; Brites,Carlos.
Nosocomial infection caused by extended-spectrum beta-lactamase producing Klebsiella pneumoniae (ESBL-Kp) have been frequently reported worldwide. We have no information on such problems in Bahia, Brazil. OBJECTIVES: Evaluate the risk factors for nosocomial infections caused by ESBL-Kp, in a tertiary hospital, in Bahia, Brazil. MATERIAL AND METHODS: We evaluated all reported cases of nosocomial infections caused by ESBL-Kp in a private, tertiary hospital, in Salvador, Brazil, from 2000 through 2004. We compared patients with a diagnosis of ESBL-Kp (cases) and patients infected by non-ESBL producing K. pneumoniae (controls). Mean age, underlying disease, and frequency of invasive procedures were compared between the two groups. History of previous use of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nosocomial infections; ESBL; Klebsiella pneumoniae; Bacterial resistance.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000300007
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Type IV SCCmec found in decade old Brazilian MRSA isolates BJID
Reinert,Cristina; McCulloch,John Anthony; Watanabe,Shinya; Ito,Teruyo; Hiramatsu,Keiichi; Mamizuka,Elsa Masae.
Methicillin-resistant Staphylococcus aureus (MRSA) commonly causes infection in hospitalized patients. Since its appearance in the 1960s, the SCCmec has evolved throughout the years into 5 different types (I-V), each bearing a different set of genes. Infection with MRSA SCCmec types I, II or III is almost exclusively restricted to hospitalised patients. However, recently, community acquired MRSA (CA-MRSA) infections have been reported with increasing frequency, usually caused by a type IV SCCmec MRSA in nosocomial settings. We studied the prevalence of SCCmec types in 50 nosocomial strains collected from 1995 to 1999. The SCCmec complex type and presence of Panton-Valentine leukocidin (PVL) were determined by PCR. Strains had been previously typed by PFGE...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nosocomial infections; Type IV SCCmec; Staphylococcus aureus; Methicillin-resistant; Brazil.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300010
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Vancomycin-resistant van a phenotype Enterococcus faecalis: first case in Minas Gerais state and epidemiological considerations BJID
Ribas,Rosineide Marques; Darini,Ana Lúcia da Costa; Moreira,Tomaz Aquino; Freitas,Claudete; Gontijo Filho,Paulo P..
We report the first case of vancomycin-resistant Enterococcus faecalis with VanA phenotype and vanA genotype isolated from a surgical patient in a general Hospital in Uberlândia, state of Minas Gerais, Brazil.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Nosocomial infections; Antibiotic resistance; VRE.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000400015
Registros recuperados: 16
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